http://www.heartwormsociety.org

Weight of Dog

Enter Animal's Weight lbs 20 kg
Prednisone Dose mg10.0Initial dose given BID and taper
Doxycycline Dose mg200.0
Melarsomine Dose mg50.0
Create a Treatment Plan

Heartworm Life Cyle
Courtesy of Bayer HealthCare, LLC | Video Length: 3:36

Heartworm Treatment Plan


1. Dog diagnosed and verified as heartworm positive

  • Positive antigen (Ag) test verified with 2nd Ag or microfilaria (MF) test
  • Clinical signs with one positive Ag test and MF test (for status)
2. Begin exercise restriction
  • The more pronounced the symptoms, the stricter the exercise restriction.
3. If the dog is symptomatic:
  • Stabilize with appropriate therapy and nursing care
  • Prednisone prescribed at 0.5 mg/kg BID 1st week, 0.5 mg/kg SID 2nd week, 0.5 mg/kg EOD 3rd and 4th week


1. Administer heartworm preventive

  • If microfilariae are present, pretreat with antihistamine and/or glucocorticosteroid if not already on prednisone to reduce anaphylaxis risk.
  • Observe for at least 8 hours for signs of reaction

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1. Doxycycline 10 mg/kg BID for 4 weeks


1. Administer heartworm preventive


1. 1st melarsomine injection 2.5 mg/kg intramuscularly (IM)

  • Rx prednisone 0.5 mg/kg BID 1st week, 0.5 mg/kg SID 2nd week, 0.5 mg/kg EOD 3rd and 4th week
2. Decrease activity level even further: Cage restriction/on leash when using yard
3. Administer heartworm preventive


1. 2nd melarsomine injection 2.5 mg/kg IM
2. Administer heartworm preventive


1. 3rd melarsomine injection 2.5 mg/kg IM

  • Rx prednisone 0.5 mg/kg BID 1st week, 0.5 mg/kg SID 2nd week, 0.5 mg/kg EOD 3rd and 4th week
2. Continue exercise restriction for 6 to 8 weeks following last injections


1. Test for presence of microfilariae

  • If positive treat with a microfilaricide and retest in 4 weeks.
2. Establish year-round heartworm prevention


1. Antigen test 6 months after completion

Additional Notes

* This At-Home Treatment Plan is only meant to serve as a guide. Please consult your veterinarian for important information about the treatment and prevention of Heartworm Disease.